Study Finds New Way to Clear Cholesterol from Blood

Scientists led by Prof David Ginsburg of the University of Michigan’s Howard Hughes Medical Institute inhibited the action of a gene responsible for transporting a protein that interferes with the ability of the liver to remove cholesterol from the blood in mice. Trapping the destructive protein where it couldn’t harm receptors responsible for removing cholesterol preserved the liver cells’ capacity to clear plasma cholesterol from the blood, but did not appear to otherwise affect the health of the mice.

In the research, scientists found that mice with an inactive SEC24A gene could develop normally. However, their plasma cholesterol levels were reduced by 45 percent because vesicles from liver cells were not able to recruit and transport a critical regulator of blood cholesterol levels called proprotein convertase subtilisin/kexin type 9 (PCSK9).

PCSK9 is a secretory protein that destroys the liver cells’ receptors of low-density lipoprotein (LDL, the so-called ‘bad cholesterol), and prevents the cells from removing the LDL.

“Inhibiting SEC24A or PCSK9 may be an alternative to statins, and could work together with statins to produce even greater effects,” said first study author Dr Xiao-Wei Chen from the Howard Hughes Medical Institute. “Also, they might be effective on patients who are resistant to or intolerant of statins.”

Initial studies of anti-PCSK9 therapies in humans have shown that eliminating PCSK9 can lower cholesterol dramatically and work with statins like Lipitor to lower it even further. The new study points to a new area for study: rather than inhibiting PCSK9 itself, perhaps future therapies could block the transport mechanism that allows the destructive protein to reach the LDL receptors.

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Sen. Mike Lee: Gun Bill Contains ‘Tomorrow’s Loopholes’

photo credit: gage skidmore

Republican Sen. Mike Lee, of Utah, said Sunday he will not support the gun-control legislation being authored in the Senate because it contains loopholes and imposes limits on law-abiding gun owners.

Lee, appearing on NBC’s “Meet the Press,” said despite the national tragedy at Sandy Hook Elementary School in December of 2012, politicians’ efforts to do the right thing have resulted in a flawed approach.

“Following the tragedy at Sandy Hook, Americans have been rightfully focused on how to prevent such tragedies from occurring in the future,” he said. “But unfortunately, the proposals we’ve seen would serve primarily to limit the rights of law-abiding citizens while doing little, if anything, to actually prevent tragedies like this from occurring in the future.”

Lee said he “can’t support” the bill named after Pennsylvania Sen. Pat Toomey and West Virginia Sen. Joe Manchin.

Read more from this story HERE.

Obama’s ‘Tax Freedom Day’ Was March 5…the Average American’s Isn’t Until April 18

photo credit: osipovva

As TheBlaze reported on Friday, President Barack Obama and wife Michelle paid 18 percent in taxes for 2012. That 18 percent tax rate means the Obamas worked just more than 64 days in order to earn the money they needed to pay the government their “fair share.”

The top tax rate charged by the federal government for high earners like the Obamas would be 35 percent. If the president and his wife paid the 35 percent rate, they would have had to work until May 8 (128 days) in order to meet their obligation to the nation.

But is 18 percent really a fair share for the first family? Let’s remember the 2012 presidential campaign that regularly featured many media outlets slamming Mitt Romney for paying around 15 percent in taxes in 2011.

It also should be noted that today, the average American has to work until April 18 in order to pay their tax obligations to the nation. (And according to one online report, April 18 is a full five days longer than last year’s Tax Freedom Day.) By the way, from January 1 to April 18 is 108 days.

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The US Abortion Lobby is 'Engaged in a Pedophile Protection Racket'

Photo Credit: WND

In what has been called the worst child sex abuse scandal in American history, the abortion industry could soon find itself beleaguered by multiple lawsuits from trial lawyers representing hundreds of thousands of victims of statutory rape.

“The abortion lobby is engaged in a pedophile protection racket and protecting pedophiles who rape underage girls,” Mark Crutcher, founder of Life Dynamics, said. “These abortion clinics receive money from the federal government. We are literally paying for the rape of our young daughters.”

Life Dynamics conducted extensive research into why 60-80 percent of teen pregnancies were the result of being impregnated by an adult.

“We realized that something had to have accounted for how this occurred beneath the radar to the point where no one except those who study it would know about it,” he explained. “The only way this could happen is if the institutions and the entities out there who should be reporting this were not doing so. We talked to people we knew in the medical community who worked in environments where they would have access to children or worked in the emergency room hospitals and started asking them about it.”

He said they quickly discovered the problem was not in the hospitals, but in the vast numbers of abortion clinics around the country where employees and managers were ignoring state laws mandating they report instances of possible child abuse to law-enforcement.

Read more from this story HERE.

1,500 Page Immigration Bill to Drop One Day Before Only Hearing?!

Photo Credit: AP

According to an ABC News report, senators from the bipartisan “Gang of Eight” pushing immigration reform are expected to drop their bill, estimated at around 1,500 pages, on Tuesday, mere hours before the only scheduled Senate hearing on the topic.

“A bipartisan group of senators plans to introduce its long-awaited immigration bill on Tuesday, Senate sources confirmed to ABC News,” Jim Avila and Jordan Fabian wrote on Friday. “Four Democrats and four Republicans, known as the ‘Gang of Eight,’ wrapped up months of hard-fought negotiations this week and will put forth a bill that includes a pathway to citizenship for many of the 11 million undocumented immigrants living in the U.S.”

If the Senators actually do wait until Tuesday to roll out their lengthy proposed overhaul of the U.S. immigration system, that will give members of the Senate Judiciary Committee less than a full day to read it before the only Senate hearing on the topic. Despite ardent pleas from Senate conservatives, including ranking Senate Judiciary Committee member Sen. Chuck Grassley, the committee’s chairman, Sen. Pat Leahy, has only agreed to one hearing on the legislation.

Leahy scheduled that single hearing for Wednesday at 2:30 PM, and the hearing’s sole scheduled witness is Department of Homeland Security Secretary Janet Napolitano. Napolitano would have less than a full day to read the bill she is scheduled to testify about.

“Gang of Eight” member Marco Rubio (R-FL) has said he supports multiple hearings and an open and transparent immigration reform process, but his actions do not necessarily back his words. He has not pushed Leahy to force multiple hearings; he appears content with the single hearing Leahy has scheduled on the issue and now appears to be backing down from his demand for multiple hearings.

Read more from this story HERE.

Rep. Stockman: Senate's Gun Control Bill Unconstitutional, We'll Kill it in the House and Send You Packing in a U-Haul

Photo Credit: Stockman

Congressman Steve Stockman Wednesday reinforced his intentions to use a “blue slip” to kill any Senate anti-gun bill that contains expanded background checks.

Stockman will also deliver U-Haul gift cards to the offices of Mark Begich, Mark Pryor, Mary Landrieu, Kay Hagan and Max Baucus should they vote for the package, to help with move-out expenses after they are defeated by voters in 2014.

“A requirement to make citizens submit to a background check imposes a tax. Such legislation cannot originate in the Senate. The bill is automatically unconstitutional,” said Stockman.

“Constitutional rights don’t require permission slips. If you infringe upon the Second Amendment’s absolute protections, you will be removed from office,” said Stockman. “The language of the Second Amendment is perhaps the starkest and most absolute in the Constitution. ‘The right of the people to keep and bear arms shall not be infringed.’ That means any obstacle whatsoever is strictly prohibited. The right to keep and bear arms cannot even be approached.”

“Criminals nationwide are applauding Joe Manchin and Pat Toomey,” said Stockman. “Joe Manchin and Pat Toomey want to give the federal government the name and address of everyone who buys a gun. They want to turn our entire country into Chicago.”

Read more from this story HERE.

Obama’s Growth-Busting Budget: Republicans Must Not Get Suckered

By Larry Kudlow. No matter how you slice the Obama budget pie, the inescapable fact is that the president wants to get rid of the roughly $1 trillion budget-cutting sequester and substitute in a $1 trillion-plus tax hike. In other words, more spending, more taxing. Growth-busting. The GOP should just say no.

And let me provide some counsel to my Republican friends in Washington, in particular in the House. Balanced budgets don’t create growth. This mantra is wrong. It’s growth that creates balanced budgets.

Cut spending? That’s a pro-growth measure. Lower tax rates? Another pro-growth measure. The combination of limited government and true tax reform will balance the budget soon enough, with government coming in at a smaller share of gross domestic product while sufficient investment and work incentives get growth moving toward the 4 or 5 percent range.

That kind of growth would make up for the lost ground of the past 15 years. And if you add in deregulation and a sound King Dollar, you’d have a growth budget that would propel America back into prosperity.

Indeed, with some tweaking of eligibility requirements, a true economic-growth budget would lower food stamp enrollment, unemployment compensation, disability benefits and other forms of welfare-dependency spending that plague the country. Medicare is a more complex issue, but Social Security would be solved by a long-run growth spurt. Read more from this story HERE.

Obama budget ‘compromise?’ No way, says the GOP

By Brad Knickerbocker. The budget President Obama delivered to Congress this week was presented as a compromise package, a path to some sort of “grand bargain” involving taxes and spending.

“I don’t believe that all these ideas are optimal,” the president acknowledged. “But I’m willing to accept them as part of a compromise if and only if they contain protections for the most vulnerable Americans.”

Indeed, his budget did draw immediate sniping from Obama’s liberal base as well as from Republican lawmakers. A particular affront to the left is the tweaking envisioned for Medicare, revealed Friday in congressional testimony by Health and Human Services Secretary Kathleen Sebelius.

The Obama budget also would change the way inflation is figured for Social Security recipients, and it raises taxes on higher-income households. But “compromise?” No way, the GOP charged in its Saturday radio/Internet address.

Speaking on behalf of her party, freshman Rep. Jackie Walorski (R) of Indiana called it “a blank check for more spending and more debt.” “Even when the president’s budget offers signs of common ground – like modest entitlement reforms – he says he won’t follow through unless he can impose more tax increases,” Rep. Walorski said. “Worst of all, the White House says the president’s budget never balances – ever, failing to meet the most basic principle of budgeting for every family and small business.” Read more from this story HERE.

Union Boss Confronts AFL-CIO on Amnesty

Photo Credit: The Washington TImes

The chief of the labor union that represents immigration agents on Friday accused the AFL-CIO, his parent organization, of “threatening” those who oppose legalizing illegal immigrants.

Chris Crane, president of the National Immigration and Customs Enforcement Council, which represents ICE agents and which is part of the AFL-CIO, said he was worried about threats of “union retribution” against lawmakers who vote against legalization this year.

His criticism underscores a fascinating split within the labor community as Congress prepares to debate immigration. Most labor unions back the push to grant legal status and citizenship rights to illegal immigrants, but the unions representing immigration law enforcement are generally opposed to that policy.

Read more from this story HERE.

NY Town Removes Veterans' Gadsden Flag for Being 'Offensive' Tea Party Symbol

Photo Credit: The Blaze

A veterans organization in a New York town is fighting for its right to fly a patriotic flag after the city council refused to let the group display the flag, calling it a symbol of the Tea Party with right-wing connotations.

The United Veterans Memorial & Patriotic Association replaced a tattered American flag at the New Rochelle Armory, flying the Gadsden flag underneath it. The bright yellow “Don’t Tread On Me” flag has been used by the Navy and Marine Corps since 1775.

When a city council member complained to the city manager that he found the flag offensive, the city manager initially decided to let the flag fly anyway. But the city council overruled him, and the flag was taken down. On Wednesday, the council voted 5 to 2 to keep the veterans from putting the flag back up.

The council objected to the flag because they said Peter Parente, the president of the veterans group, is a member of the Tea Party and the group wants to use the flag to make a political point.

But Parente said at the council meeting no one in his organization is a Tea Party member.

Read more from this story HERE.

Rep. Chris Smith: 'If Gosnell had shot Seven Infants with an AR-15 it would be National News'

Photo Credit: Reuters

Thanks to conservative new media, the Kermit Gosnell trial is finally part of the national dialog. But before the mainstream press got around to doing their job, ten congressmen took to the floor of the House to protest the lack of media attention being paid to the horrifying story. One such congressman, Rep. Chris Smith (R-NJ), contrasted the abortionist’s trial to another ongoing narrative that the media covers obsessively: gun control. “If Dr. Gosnell had walked into a nursery and shot seven infants with an AR-15, it would be national news and the subject of presidential hand-wringing,” said Smith, a member of the House pro-life caucus.

LifeSiteNews reports that Smith accused the national media of almost uniformly discounting the trial of the abortionist who allegedly snipped the spinal cords of babies who were born alive during abortion procedures in his clinic. Smith referred to the media’s decision to ignore the trial as a deliberate “cover-up.”

“Will the decades-long major national news media cover-up of the brutality—and violence—of abortion methods ever end?” asked Smith. “Will Americans ever be told the horrifying details as to how—and how often—abortionists dismember, decapitate, and chemically poison innocent babies?”

Smith went on to ask, “Murdering newborns in the abortion clinic, it seems to me, is indistinguishable from any other child predator wielding a knife or a gun. Why isn’t that child seen as a patient in need of medical care, warmth, nutrition and dare I say—love?”

Testimony in the Gosnell trial, that has included descriptions of gruesome acts of beheadings, abuse, death, and body parts of babies in jars, has led to the abortionist’s clinic being labeled a “house of horrors.”

Read more from this story HERE.