One Popular COVID Vaccine Found More Effective Against Delta Variant

Early findings posted ahead of rigorous peer review suggested the Pfizer COVID-19 vaccine declined to 42% effectiveness against infection amid sweeping spread of the delta variant, with the Moderna vaccine declining to 76%.

Researchers at the Mayo Clinic and Cambridge-based biotech company nference posted the retrospective study in medrxiv this week, drawing from tens of thousands PCR tests conducted at the Mayo Clinic and affiliated hospitals across nearly half a dozen states.

The study period analyzed samples from January to July, when either the alpha or delta variant was a highly prevalent strain; “the Delta variant prevalence in Minnesota increased from 0.7% in May to over 70% in July whereas the Alpha variant prevalence decreased from 85% to 13% over the same time period,” the preprint reads.

While results indicated the Pfizer and Moderna vaccines were highly effective against COVID-19 infection (76%, 86%, respectively) and hospitalization (85%, 91.6%) the effectiveness against infection dropped by July to 42% and 76%, respectively.

Further findings indicated that people vaccinated with Moderna’s shot were half as likely to develop a breakthrough infection, compared to recipients of the Pfizer vaccine. What’s more, researchers found that Florida residents fully vaccinated with Moderna’s shot faced a 60% lower risk of infection when compared to Pfizer recipients. Also, across all states, the Moderna vaccine cut COVID-related hospitalizations by about half the rate compared to the Pfizer vaccine. Researchers noted “no significant difference” between the groups relating to ICU admission for COVID-19. (Read more from “One Popular COVID Vaccine Found More Effective Against Delta Variant” HERE)

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